San Francisco 49ers running back Christian McCaffrey (23) celebrates his touchdown against the Atlanta Falcons in the first half of an NFL football game, Sunday, Oct. 19, 2025, in Santa Clara, California. (AP Photo/Godofredo A. Vásquez)
Monday Night Football is back, and tonight we have a cross-country battle as we see Washington take on San Francisco. Fanatics is getting you in on the action with promo code FOXNEWS350. New users can wager $20 on tonight’s game using promo code FOXNEWS350 to earn $350 in FanCash.
This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX News may be compensated. This content was created by a team that works independently from the FOX newsroom.
How to Sign Up and Claim the Fanatics Sportsbook Welcome Bonus
- Visit Fanatics Sportsbook by clicking the applicable “Claim Bonus” button on this page.
- Create a new account and complete account registration, KYC and exchange account verification.
- Once your account is verified, deposit at least $20 into your account.
- Use promo code FOXNEWS350
- Place a $20 wager on tonight’s game
- Receive $350 in FanCash after your wager is graded.
- For more information, review the Fanatics Sportsbook promo page
Commanders vs. 49ers, Monday, October 19, 2026 at 8:15 ET | Levi’s Stadium, Santa Clara, CA | ESPN/ABC
Coming into tonight, the two teams, the Commanders and 49ers, are on vastly different trajectories. The Commanders are 1-3-1 for the season, and the 49ers are 5-0. Washington desperately needs a win, and San Francisco, well, doesn’t. If the 49ers were to lose, it probably would just be a head-scratching blemish on what looks to be a great season.
The Commanders started their season with a loss against the Eagles. They had to travel on the road to face Philadelphia. The final score was close, but the reality is that Philly was in control most of the game. In Week 2, they were dismantled by Dallas, and starter Jayden Daniels left the game early. They got their lone win against the Seahawks in their home opener. Marcus Mariota was under center for that one and the next week’s loss against the Colts. Last week, Daniels returned, but they lost to the Giants.
The 49ers have had a tougher schedule, but have navigated it very well. They opened against the preseason consensus favorite for the Super Bowl, the Rams. They destroyed Los Angeles 27-7 in the Australian game. Weeks 2 and 3 were against bad teams, the Dolphins and the Cardinals. San Francisco had a bit easier of a time with the Dolphins than the Cardinals, but prevailed in each. In the past two weeks, they’ve beaten the Broncos and Seahawks, both Super Bowl hopefuls.
Will the 49ers get the win here and stay perfect, or will the Commanders get a much-needed upset? You make the call on Fanatics Sportsbook. Bet $20 on the game and earn $350 in FanCash when new users sign up with code FOXNEWS350.
Commanders vs. 49ers Odds
Odds subject to change
| Spread | Total | Moneyline | |
| Commanders | +7.5 (-110) | O 52.5 (-105) | +350 |
| 49ers | -7.5 (-110) | U 52.5 (-115) | -455 |
